What can I say? The pictures are beautiful, but German is a horrible language
From what I understood:
-the main story will be more explicit than in G3 to avoid the situation that the player gets lost in hundreds of small quests that don't have anything to do with it
-more detailed quest log
-there will be many women, probably the first person you meet is female
-the architecture will be inspired by Khorinis and "how did the Varant ruins looks before they were ruined"
-a strange force, stronger even than Beliar and Innos, is possessing Nameless, and that's the reason no one likes him anymore